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Parylene for use in Bio-Medical implantable devices

Posted by Sean Horn

Tuesday, June 12, 2012 10:52

@ 10:52 AM

Whenever implantable devices come into contact with the human body, long term protection against body fluids, enzymes, proteins, and lipids is vital.  Bio-medical surfaces typically require coating to protect from moisture, chemicals, and other potentially harmful substances.

A downfall for wet chemistry, liquid coatings such as silicones, acrylics, epoxy, or urethanes is that they do not meet bio-compatibility requirements and cannot be applied with precise control.  On the contrary, parylene does not out-gas and is very effective against the passage of contaminants from both the body to substrate or substrate to body.

Parylene can be applied a couple of mils thick to a few hundred angstroms in thickness, it is pin hole free, applied at room temperature, contains no additives, insoluble in most solvents, very lubricious, has a very high dielectric strength, and is biocompatible and bio-stable.

Parylene C is currently being used is a number of well documented bio-medical implantable devices.  Parylene C has been proven to be a terrific biocompatible material.  It is USP Class VI implantable plastic material and conforms to material ISO-10993 Biological Evaluations for Medical Applications.  Parylene C is also probably the longest proven protective biocompatible material.

Download Our Guide on Parylene 101


Parylene Technology for Neural Probes Applications.  Changlin Pang.  California Institute of Technology.  2008.


S. Nancy, “Literature Review: Biological Safety of Parylene C,” Medical Plastics

and Biomaterials, vol. 3, pp. 30-35, March 1996.


B. Humphrey, “Using Parylene for Medical Substrate Coating,” Medical Plastics

and Biomaterials, Janurary 1996.


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